In contrast, while the dose-response relationship between -cell responsiveness to glucose (expressed as the slope of the linear relation between insulin secretion rate and the glucose concentration) and GLP-1 levels in circulation is partially impaired a phenomenon referred as GLP-1 resistance (62) a therapeutic infusion of GLP-1 at a pharmacological dose can restore -cell insulin secretion responsiveness to glucose levels comparable to those observed in nondiabetic individuals (62)
Rosenstock J, Allison D, Birkenfeld AL, Blicher TM, Deenadayalan S, Jacobsen JB, Serusclat P, Violante R, Watada H, Davies M, PIONEER 3 Investigators
The bottom line: shifts in libido and sexual function on GLP-1 medications are not only possible, theyre worth paying attention to and discussing
Id recommend you divide your current body weight by 2.2, then multiply it by 1.6
The maintenance of the mucus layer that protects the intestinal epithelium is a vital function of gut bacteria
All providers advise patients to seek emergency care for serious side effects such as signs of pancreatitis, severe allergic reactions, or other emergency symptoms